Exploring genome, transcriptome, and microbiome interactions related to feed efficiency and methane emissions in Bos indicus through multi-omics network analysis.

doi:10.1007/s00335-025-10160-w

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Exploring genome, transcriptome, and microbiome interactions related to feed efficiency and methane emissions in Bos indicus through multi-omics network analysis.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Dec 2025

Cardoso Tainã Figueiredo, Bruscadin Jennifer Jessica, Afonso Juliana, Conteville Liliane Costa, Andrade Bruno Gabriel Nascimento, Malheiros Jessica Moraes, Fernandes Anna Carolina, Diniz Wellison J S, Banerjee Priyanka, de Oliveira Priscila S N, Zerlotini Adhemar, Mourão Gerson Barreto, Coutinho Luiz Lehmann, Regitano Luciana Correia de Almeida

Abstract excerpt

The minor effects of many SNP interactions often determine complex traits. This interaction, known as epistasis, represents a non-additive genetic effect in which the influence of one variant depends on the presence of others. In this study, we tested for epistatic effects on the residual feed intake (RFI) and residual methane emission (RME) traits of Nelore cattle. Additionally, we evaluated the impact of these...

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PMID: 40999243
DOI: 10.1007/s00335-025-10160-w

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