Folate disorder in the atdfb mutant triggers a compensatory nitrogen starvation response by altering nitrate transport and assimilation.

Abstract excerpt

Folates are essential cofactors that bridge carbon and nitrogen metabolism. However, the role of specific folate derivatives in regulating nitrogen homeostasis remains poorly understood. Here, we characterize the link between folate metabolism and nitrogen sensing using the Arabidopsis thaliana atdfb mutant. We show that atdfb exhibits a disrupted folate profile, characterized by a deficiency in main metabolic...

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