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Article

Immunosenescence phenotypes and prognostic significance of CD8 + CD28- T cells in AIDS-related non-Hodgkin lymphoma.

Annals of medicine - 1 Dec 2025

Kang Zixin, Tao Xin, Wu Shuting, Chu Shuai, Peng Jie, Chen Juanjuan

Abstract excerpt

BACKGROUND: AIDS-related non-Hodgkin lymphoma (AR-NHL), a leading malignancy among people living with HIV (PLWH), may not receive standard intensive curative therapies as the general population due to immune deficiency concerns, even in the combined antiretroviral therapy (cART) and immunochemotherapy era. Thus, a comprehensive understanding of T-cell subsets landscapes is urgently needed to grasp the complex and...

Read the complete abstract on PubMed

Topics

Humans
Male
Female
Middle Aged
Immunosenescence
Adult
Lymphoma, Non-Hodgkin

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Prognosis

CD8-Positive T-Lymphocytes

Longitudinal Studies

CD28 Antigens

Lymphoma, AIDS-Related

Phenotype

Immunophenotyping

Source

Open in PubMed Open full text

Identifiers

PMID: 40932058
DOI: 10.1080/07853890.2025.2558123
PMCID: PMC12427475

Genes

AR
CD28
CD4

Provenance

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