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Article

Intergenerational continuity of depressive symptoms: genetic and environmental pathways.

Psychological medicine - 8 Sept 2025

Navarro Marie C, de Roo Marthe, Oldehinkel Albertine J, Hartman Catharina A, Kretschmer Tina

Abstract excerpt

BACKGROUND: Depression runs in families, with both genetic and environmental mechanisms contributing to intergenerational continuity, though these mechanisms have often been studied separately. This study examined the interplay between genetic and environmental influences in the intergenerational continuity of depressive symptoms from parents to offspring. METHODS: Using data from the Dutch TRAILS cohort...

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Identifiers

PMID: 40916708
DOI: 10.1017/S0033291725101633
PMCID: PMC13040585

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