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Article

Uncovering the role of genetic polymorphisms in cervical insufficiency.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics - 1 Mar 2026

Kalinderi Kallirhoe, Kalinderis Michail, Chatzidimitriou Maria, Fidani Liana

Abstract excerpt

Cervical insufficiency (CI) is characterized by spontaneous dilation of the cervix in the absence of painful uterine contractions in the mid-trimester, leading to premature delivery. It is responsible for up to 20% of second trimester pregnancy losses, mostly <24 weeks. This life-threatening condition for the growing fetus faced during pregnancy is of complex etiology. The genetic background of this disorder is...

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Identifiers

PMID: 40905107
DOI: 10.1002/ijgo.70494
PMCID: PMC12936634

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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