Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Knockoff-Based Fine Mapping of MS-Associated SNPs in Sardinian Trios.

Biochemical genetics - 1 Jun 2026

Baldrighi Giulia Nicole, Nova Andrea, Ekstrøm Claus Thorn, Piras Maria Luisa, Saddi Maria Valeria, Bernardinelli Luisa, Fazia Teresa

Abstract excerpt

Genetic predisposition plays a key role in autoimmune and complex diseases such as multiple sclerosis (MS). However, identifying the specific variants or genomic regions responsible for disease susceptibility remains a significant challenge. In this study a family-based fine mapping approach was applied to analyze 142 trios, aiming to identify associated genetic variants linked to MS. The targeted genomic region...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acid Sensing Ion Channels
Share to Chromosome Mapping

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Linkage Disequilibrium

Share to Multiple Sclerosis

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 40884622
DOI: 10.1007/s10528-025-11238-5
PMCID: PMC13186870

Genes

ASIC2
MYO1D

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Knockoff-Based Fine Mapping of MS-Associated SNPs in Sardinian Trios.PMID 40884622Read ↗

Homozygosity Haplotype and Whole-Exome Sequencing Analysis to Identify Potentially Functional Rare Variants Involved in Multiple Sclerosis among Sardinian Families.Semantic proximity Read ↗

Investigating multiple sclerosis genetic susceptibility on the founder population of east-central Sardinia via association and linkage analysis of immune-related loci.Semantic proximity Read ↗

Genetic analysis of the isolated Faroe Islands reveals SORCS3 as a potential multiple sclerosis risk gene.Semantic proximity Read ↗

Whole exome sequencing in multi-incident families identifies novel candidate genes for multiple sclerosisSemantic proximity Read ↗

Genetics of multiple sclerosis: swimming in an ocean of data.Semantic proximity Read ↗

Genetic and molecular architecture of multiple sclerosis in gulf cooperation council populations: A scoping review and regional precision-neurology perspective.Semantic proximity Read ↗

Enrichment for Northern European-derived multiple sclerosis risk alleles in Sardinia.Semantic proximity Read ↗

Replication analysis of variants associated with multiple sclerosis risk.Semantic proximity Read ↗

Whole Exome Sequencing in Multi-Incident Families Identifies Novel Candidate Genes for Multiple Sclerosis.Semantic proximity Read ↗

Multilocus evaluation of genetic predictors of multiple sclerosis.Semantic proximity Read ↗

Elevated genetic risk for multiple sclerosis originated in Steppe Pastoralist populationsSemantic proximity Read ↗

A whole genome association study in Icelandic multiple sclerosis patients with 4804 markers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.