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Mapping evolutionary paradigm of bovine viral diarrhea virus Npro associated with different organizations of nucleotide

29 Aug 2025

Abstract excerpt

The non-structural protein (Npro) of bovine viral diarrhea virus (BVDV) is a crucial virulence factor that impairs the host’s antiviral immune response and facilitates virus production. This study establishes a foundation for understanding how different selective pressures influence the formation of nucleotide pairs, synonymous codon, and context-dependent codon bias (CDCB) in BVDV Npro. BVDV genotype 1 exhibits...

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PMID: 40879629
DOI: 10.1080/21505594.2025.2550620

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