Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Skin metatranscriptomics reveals a landscape of variation in microbial activity and gene expression across the human body

28 Aug 2025

Abstract excerpt

Metatranscriptomics methods for the skin are hampered by low microbial biomass, contamination with host cells and low RNA stability. In this study, we developed a robust, clinically tractable skin metatranscriptomics workflow that provides high technical reproducibility of profiles, uniform coverage across gene bodies and strong enrichment of microbial mRNAs. Paired application of this protocol with metagenomics...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dermatology and Skin Diseases
Share to Gut microbiota and health
Share to Single-cell and spatial transcriptomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40877570
DOI: 10.1038/s41587-025-02797-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Skin metatranscriptomics reveals a landscape of variation in microbial activity and gene expression across the human bodyPMID 40877570Read ↗

Skin metatranscriptomics reveals landscape of variation in microbial activity and gene expression across the human bodySemantic proximity Read ↗

A mixed community of skin microbiome representatives influences cutaneous processes more than individual membersSemantic proximity Read ↗

A Mixed Community of Skin Microbiome Representatives Influences Cutaneous Processes more than Individual MembersSemantic proximity Read ↗

Experimental metagenomics and ribosomal profiling of the human skin microbiomeSemantic proximity Read ↗

Microbe-host interplay in atopic dermatitis and psoriasisSemantic proximity Read ↗

Metagenomic Studies in Inflammatory Skin DiseasesSemantic proximity Read ↗

Evolving approaches to profiling the microbiome in skin diseaseSemantic proximity Read ↗

The skin microbiome: potential for novel diagnostic and therapeutic approaches to cutaneous diseaseSemantic proximity Read ↗

SkinCom, a synthetic skin microbial community, enables reproducible investigations of the human skin microbiomeSemantic proximity Read ↗

Skin microbiota in health and disease: From sequencing to biologySemantic proximity Read ↗

Integrating cultivation and metagenomics for a multi-kingdom view of skin microbiome diversity and functionsSemantic proximity Read ↗

The Skin Microbiome: Current Techniques, Challenges, and Future DirectionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.