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Characterizing influenza A virus lineages and clinically relevant mutations through high-coverage wastewater sequencing.

Water research - 1 Dec 2025

John Anika, Kang Seju, Fuhrmann Lara, Topolsky Ivan, Kent Christopher, Quick Joshua, Stadler Tanja, Julian Timothy R, Beerenwinkel Niko

Abstract excerpt

Influenza A virus poses significant public health challenges, causing seasonal outbreaks and pandemics. Its rapid evolution motivates continuous monitoring of circulating influenza genomes to inform vaccine and antiviral development. Wastewater-based surveillance offers an unbiased, cost-effective approach for genomic surveillance. We developed a novel tiling amplicon primer panel that covers diversity of...

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PMID: 40865342
DOI: 10.1016/j.watres.2025.124453

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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