Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of neoadjuvant targeted therapy on the tumor microenvironment in resectable lung adenocarcinoma.

Cellular oncology (Dordrecht, Netherlands) - 1 Oct 2025

Yi Ling, Yao Heng, Bai Zhexin, Xu Ziwei, Li Huimin, Cheng Yuting, Wang Chong

Abstract excerpt

BACKGROUND: Neoadjuvant targeted therapy has emerged as a promising strategy for resectable non-small cell lung cancer (NSCLC). The analysis of the immune status of tumor microenvironment (TME) after targeted therapies is crucial for understanding the impact of targeted therapy on the TME and providing a basis for synergistic therapeutic approaches. METHODS: Forty-two patients with resectable lung adenocarcinoma...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma of Lung
Share to Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ErbB Receptors

Share to Lung Neoplasms

Share to Molecular Targeted Therapy

Share to Mutation

Share to Neoadjuvant Therapy

Share to Tumor Microenvironment

Source

Open in PubMed Open full text

Identifiers

PMID: 40864402
DOI: 10.1007/s13402-025-01101-5
PMCID: PMC12528237

Genes

ALK
EGFR
GZMB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of neoadjuvant targeted therapy on the tumor microenvironment in resectable lung adenocarcinoma.PMID 40864402Read ↗

Neoadjuvant Chemoimmunotherapy in Patients with Resectable Non-small Cell Lung Cancer.Semantic proximity Read ↗

EGFR-Mutated Non-Small Cell Lung Cancer and Resistance to Immunotherapy: Role of the Tumor Microenvironment.Semantic proximity Read ↗

The expression of PD-1 ligands in the immune microenvironment was altered in TTF-1-negative lung adenocarcinomaSemantic proximity Read ↗

Macrophage and Tumor Cell Cross-Talk Is Fundamental for Lung Tumor Progression: We Need to TalkSemantic proximity Read ↗

Characteristics of the immune microenvironment and their clinical significance in non-small cell lung cancer patients with ALK-rearranged mutation.Semantic proximity Read ↗

Neoadjuvant immunochemotherapy vs. neoadjuvant targeted therapy plus chemotherapy for EGFR-mutated non-small cell lung cancer: a retrospective study.Semantic proximity Read ↗

<p>Immunotherapy after EGFR‑TKI treatment in advanced non‑small cell lung cancer: Current status and future perspectives (Review)</p>.Semantic proximity Read ↗

Neoadjuvant PD-1 Blockade in Resectable Lung Cancer.Semantic proximity Read ↗

Tumor immune microenvironment in non-small cell lung cancer with EGFR mutation before and after EGFR-TKIs treatmentSemantic proximity Read ↗

[Influencing Factors and Significance of Tumor-associated Macrophage Polarization in Tumor Microenvironment].Semantic proximity Read ↗

Neoadjuvant immunotherapy for dMMR and pMMR colorectal cancers: therapeutic strategies and putative biomarkers of responseSemantic proximity Read ↗

[Potential Value of Neoadjuvant Immunochemotherapy in Patients with Driver Gene-positive Non-small Cell Lung Cancer].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.