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Article

Post-Translational Modifications in Mammalian Folliculogenesis and Ovarian Pathologies

20 Aug 2025

Abstract excerpt

Post-translational modifications (PTMs) of proteins, as the core mechanism for dynamically regulating follicular development, affect the maintenance of mammalian fertility by precisely coordinating granulosa cell-oocyte interaction, metabolic reprogramming, and epigenetic remodeling. Dysregulation of these modifications directly contributes to major reproductive diseases, including polycystic ovary syndrome...

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PMID: 40862771
DOI: 10.3390/cells14161292

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