Article
Neuro-ophthalmic complications of endosteal hyperostosis, Worth type: the importance of ophthalmic monitoring.
Ophthalmic genetics - 1 Dec 2025
Higham Aisling, Watts Laura M, Rao Dipesh, Wordsworth Paul, Hildebrand Darius, Johnson David, Shears Deborah
Abstract excerpt
Disorders of bone formation or resorption affecting the cranium can lead to ophthalmic complications. We describe a family with Worth endosteal hyperostosis (WEH), an autosomal dominant condition characterized by mandibular overgrowth and cortical thickening of long bones. Although traditionally considered benign, we report significant neuro-ophthalmic complications in this kindred.This retrospective case series...
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