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Article

Phenotype characterization of heart failure with preserved ejection fraction in medical device and surgical trials.

ESC heart failure - 1 Dec 2025

Araz Kurdo, Fioretti Francesco, Ladak Sara, Obaidan Mohammed, Butler Javed, Hameed Aamir

Abstract excerpt

AIMS: Heart failure with preserved ejection fraction (HFpEF) prevalence is nearing 50% of all heart failure cases and is often associated with advanced age, obesity, atrial fibrillation and hypertension, and medical approaches are limited. This review aims to determine the potential of medical devices or surgical interventions in treating HFpEF and to propose specific phenotypes of HFpEF. METHODS AND RESULTS: A...

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PMID: 40857067
DOI: 10.1002/ehf2.15401
PMCID: PMC12719810

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