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Targeting Streptococcus pyogenes atpF protein for multi-epitope vaccine development: a genomics-driven immunoinformatics strategy

5 Aug 2025

Abstract excerpt

Streptococcus pyogenes, a medium-priority pathogen on the WHO's 2024 Bacterial Pathogen Priority List, is a major cause of infectious disease-related mortality. The increasing prevalence of antibiotic resistance, coupled with the absence of a licensed vaccine due to the pathogen's genetic diversity and autoimmune concerns, underscores the need for novel therapeutic strategies. This study employs reverse...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40854665
DOI: 10.1016/j.jgeb.2025.100546

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