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PIEZO1 ‐Mediated Mechanotransduction in Craniofacial Biology

22 Aug 2025

Abstract excerpt

influx, thereby regulating pathways such as Wnt/β-catenin, NF-κB, and YAP/TAZ. It plays a pivotal role in craniofacial biology by maintaining bone homeostasis, facilitating dentin mineralization, periodontal remodeling, and orthodontic tooth movement. Expressed in bone tissue, dental pulp stem cells, and periodontal ligament cells, dysregulated PIEZO1 is implicated in a number of conditions, including...

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PMID: 40844383
DOI: 10.1096/fj.202501130r

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