Article
Schistosome Infection is Associated With High-Risk Human Papillomavirus Persistence, Together With Altered Cervicovaginal Microbiota.
The Journal of infectious diseases - 18 Feb 2026
Mukerebe Crispin, Cordeiro Alexandra A, Aristide Christine, Colombe Soledad, Bullington Brooke W, Kalluvya Samuel, van Dam Govert J, de Dood Claudia J, Corstjens Paul L A M, Maganga Jane K, Changalucha John M, Namkinga Lucy A, Makene Victor Anacletus, Lee Myung Hee, Downs Jennifer A
Abstract excerpt
Schistosoma haematobium infection may impair female genital mucosal antiviral defense. We sought to determine whether women with S. haematobium infection had higher odds of high-risk human papillomavirus (HR-HPV) persistence, a prerequisite to cervical cancer. We also examined cervicovaginal dysbiosis, which has been linked to HR-HPV persistence and schistosome infection. In 96 Tanzanian women with baseline and...
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