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Article

Development of a multiplex quantitative real-time PCR (qPCR) assay for simultaneous detection of Schistosoma haematobium and high-risk human papillomaviruses.

PLoS neglected tropical diseases - 1 Sept 2026

Donkoh Emmanuel Timmy, Williams Isaac, Akologo Rita Nyaaba, Asiedu Alfred Afriyie, Ofori-Atta Reindoff Junior, Boadu Ivy Wina, Ryabinina Oksana, Forson Akua Obeng, Boampong Kwadwo, Jain Neeraj, Dassah Edward Tieru, Gyasi Samuel Fosu, Arroyo Mühr Laila Sara, Akanwariwaik William Gariba

Abstract excerpt

BACKGROUND: Female genital schistosomiasis (FGS) and high-risk human papillomavirus (hr-HPV) infections frequently co-occur in sub-Saharan Africa and may jointly contribute to cervical carcinogenesis. However, no existing molecular platform enables simultaneous detection of Schistosoma haematobium and hr-HPV from a single cervical specimen. METHODS: A multiplex quantitative real-time PCR (qPCR) assay targeting...

Read the complete abstract on PubMed

Topics

Humans
Schistosoma haematobium
Female
Animals
Schistosomiasis haematobia

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Papillomavirus Infections

Sensitivity and Specificity

Ghana

Real-Time Polymerase Chain Reaction

Papillomaviridae

Human Papillomavirus Viruses

Multiplex Polymerase Chain Reaction

Adult

Genotype

Cervix Uteri

Coinfection

Young Adult

Middle Aged

Source

Open in PubMed Open full text

Identifiers

PMID: 42726901
DOI: 10.1371/journal.pntd.0014694
PMCID: PMC13592694

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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