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Article

Distinct Clinical Phenotypes in Lactase Nonpersistence: Symptomatic, Asymptomatic, and Gassy-Asymptomatic.

The American journal of gastroenterology - 1 Jun 2026

Azimov Michal, Cohen-Michnik Ida, Rottenstreich Moshe, Katz Lior, Zeigerman Haim, Yona Avihu H

Abstract excerpt

INTRODUCTION: Lactase deficiency allows undigested lactose to reach the colon, where fermentation triggers gastrointestinal symptoms. Although lactase persistence (LP) vs non-persistence (LNP) is genetically defined, many LNP individuals are symptoms-free, suggesting additional determinants of the phenotype. We aimed to define clinically relevant LNP subgroups and examine microbiome features that differ among...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40839081
DOI: 10.14309/ajg.0000000000003740
PMCID: PMC13225112

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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