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Article

Changes in gut microbiota and lactose intolerance symptoms before and after daily lactose supplementation in individuals with the lactase nonpersistent genotype.

The American journal of clinical nutrition - 1 Mar 2024

JanssenDuijghuijsen Lonneke, Looijesteijn Ellen, van den Belt Maartje, Gerhard Beatrix, Ziegler Martin, Ariens Renata, Tjoelker Reina, Geurts Jan

Abstract excerpt

BACKGROUND: Approximately 70%-100% of the Asian adult population is lactase nonpersistent (LNP). The literature shows that many individuals with the LNP-genotype can consume ≤12 g of lactose without experiencing gastrointestinal discomfort. Repetitive consumption of lactose may reduce intolerance symptoms via adaptation of the gut microbiota. OBJECTIVE: This study aimed to assess the effects of daily consumption...

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Identifiers

PMID: 38159728
DOI: 10.1016/j.ajcnut.2023.12.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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