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Pregnancy and Lactation Associated Bone Fragility

8 Jul 2025

Abstract excerpt

The skeleton is a storehouse of mineral that can be borrowed from in times of need, such as for reproduction. Skeletal resorption is normally modest during pregnancy but can be excessive when dietary calcium intake or absorption are insufficient for maternal and fetal needs. In contrast, substantial skeletal resorption is hormonally programmed to occur during lactation, with a loss of 5% to 10% of bone density...

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PMID: 40837111
DOI: 10.1210/jendso/bvaf126

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