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Comprehensive Multi-omics Analysis of Regulatory Variants for Body Weight in Cattle.

Genomics, proteomics & bioinformatics - 22 Sept 2025

Niu 牛群皓 Qunhao, Wu 武嘉远 Jiayuan, Wu 吴天弋 Tianyi, Zhang 张天留 Tianliu, Wang 王添祯 Tianzhen, Zheng 郑旭 Xu, Zhao 赵志达 Zhida, Xu 徐玲 Ling, Wang 王泽昭 Zezhao, Zhu 朱波 Bo, Zhang 张路培 Lupei, Gao 高会江 Huijiang, Liu George E, Li 李俊雅 Junya, Xu 徐凌洋 Lingyang

Abstract excerpt

Body weight is a polygenic trait with intricate inheritance patterns. Functional genomics enriched with multi-layer annotations offers essential resources for exploring the genetic architecture of complex traits. In this study, we conducted an extensive characterization of regulatory variants associated with body weight-related traits in cattle using multi-omics analysis. First, we identified seven candidate...

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PMID: 40824217
DOI: 10.1093/gpbjnl/qzaf067
PMCID: PMC12701805

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LAP3
MED28
NCAPG

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