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Article

Microbiota composition-based donor selection affects FMT efficacy in a murine colitis model

1 Aug 2025

Abstract excerpt

Background Growing evidence links gut microbial dysbiosis to inflammatory bowel disease (IBD) pathogenesis, establishing fecal microbiota transplantation (FMT) as a microbiota-targeted therapy; however, variable outcomes in randomized trials highlight the need to identify compositional features of donor microbiota associated with FMT efficacy. Objective This study aimed to investigate how the composition of the...

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PMID: 40821820
DOI: 10.3389/fimmu.2025.1635244

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