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Article

Microbial determinants of effective donors in faecal microbiota transplantation for UC

25 Jul 2022

Abstract excerpt

OBJECTIVE: Faecal microbiota transplantation (FMT) has variable efficacy in treating UC. Recently, oral lyophilised FMT was found to induce remission in patients with UC, with one donor having 100% efficacy compared with a second donor (36% efficacy). We characterised differences in the gut microbiota of these two donors with the aim of improving FMT donor selection. DESIGN: Faecal samples from the two donors...

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PMID: 35879048
DOI: 10.1136/gutjnl-2022-327742

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