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Article

Oesophageal dysmotility patterns are associated with distinct clinical phenotypes and prognosis in patients with systemic sclerosis.

Rheumatology (Oxford, England) - 1 Dec 2025

Alcala-Gonzalez Luis G, Guillen-Del-Castillo Alfredo, Aguilar Ariadna, Barber Claudia, Malagelada Carolina, Polo Figueras Laura, Triginer Laura, Codina-Clavaguera Claudia, Hughes Michael, Serra Jordi, Simeón-Aznar Carmen P, McMahan Zsuzsanna H

Abstract excerpt

OBJECTIVES: Oesophageal dysmotility is a common manifestation of SSc, contributing to substantial morbidity. We sought to determine whether oesophageal dysmotility patterns by high-resolution oesophageal manometry were associated with distinct SSc clinical phenotypes and different outcomes. METHODS: We analysed a cohort of SSc patients with detailed clinical and immunological data. Oesophageal motility was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40795829
DOI: 10.1093/rheumatology/keaf433
PMCID: PMC12671867

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