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Improvement of the sensitivity of circulating tumor DNA-based liquid biopsy: current approaches and future perspectives

8 Aug 2025

Abstract excerpt

Liquid biopsy (LB) is a complex of procedures aimed at the detection of tumor-derived fragments (nucleic acids, proteins, cells, etc.) persisting in the blood or other body fluids. It can be utilized for early cancer diagnosis, analysis of biomarkers of tumor drug sensitivity and prognosis, monitoring of minimal residual disease (MRD), etc. Circulating tumor DNA (ctDNA) is an accessible and reliable LB analyte as...

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PMID: 40787067
DOI: 10.37349/etat.2025.1002333

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