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Complement in antiphospholipid syndrome, time to target?

6 Aug 2025

Abstract excerpt

Antiphospholipid syndrome (APS) is an acquired autoimmune thrombophilia. Complement system, which shares common actors with the coagulation cascade, is nowadays well established to be implicated in APS pathophysiology by different mechanisms. In APS, complement activation assessment is not included in the routine care despite numerous studies showing the presence of activation fragments (C4d, C3d, and C5b9) at a...

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PMID: 40774121
DOI: 10.1016/j.coi.2025.102628

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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