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Article

Whole-genome sequencing of 490,640 UK Biobank participants.

Nature - 1 Sept 2025

Abstract excerpt

Whole-genome sequencing provides an unbiased and complete view of the human genome and enables the discovery of genetic variation without the technical limitations of other genotyping technologies. Here we report on whole-genome sequencing of 490,640 UK Biobank participants, building on previous genotyping effort1. This advance deepens our understanding of how genetics associates with disease biology and further...

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Identifiers

PMID: 40770095
DOI: 10.1038/s41586-025-09272-9
PMCID: PMC12443626

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