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Article

The gut microbiome associated with LGI1 ‐antibody encephalitis

6 Aug 2025

Abstract excerpt

OBJECTIVE: Autoimmune encephalitis is a cause of brain inflammation characterized by auto-antibodies, which target cell surface neuronal proteins and lead to neuronal dysfunction. The most common form is associated with auto-antibodies to leucine-rich glioma-inactivated 1 (LGI1) protein, the presentation of which includes frequent focal seizures. The exact cause of these auto-antibodies remains unknown, but...

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PMID: 40768327
DOI: 10.1111/epi.18556

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