Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Role of Sex in the Pathophysiology of Pulmonary Hypertension.

Advances in experimental medicine and biology - 1 Jan 2000

Docherty Craig K, Harvey Katie Yates, Mair Kirsty M, Griffin Sinead, Denver Nina, MacLean Margaret R

Abstract excerpt

Pulmonary arterial hypertension (PAH) is a progressive disease characterised by increased pulmonary vascular resistance and pulmonary artery remodelling as result of increased vascular tone and vascular cell proliferation, respectively. Eventually, this leads to right heart failure. Heritable PAH is caused by a mutation in the bone morphogenetic protein receptor-II (BMPR-II). Female susceptibility to PAH has been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antihypertensive Agents
Share to Arterial Pressure

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bone Morphogenetic Protein Receptors, Type II

Share to Gonadal Steroid Hormones

Share to Hypertension, Pulmonary

Share to Pulmonary Artery

Share to Receptors, Estrogen

Share to Vascular Remodeling

Source

Identifiers

PMID: 30051404
DOI: 10.1007/978-3-319-77932-4_31

Genes

PAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Role of Sex in the Pathophysiology of Pulmonary Hypertension.PMID 30051404Read ↗

Sex differences in pulmonary (arterial) hypertension: does it matter?Semantic proximity Read ↗

Roles of Genetic Predisposition in the Sex Bias of Pulmonary Pathophysiology, as a Function of Estrogens : Sex Matters in the Prevalence of Lung Diseases.Semantic proximity Read ↗

Sex Dimorphism in Pulmonary Hypertension: The Role of the Sex ChromosomesSemantic proximity Read ↗

[Female gender and pulmonary arterial hypertension: a complex relationship].Semantic proximity Read ↗

Sex-biased TGFβ signalling in pulmonary arterial hypertensionSemantic proximity Read ↗

The serotonin transporter, gender, and 17β oestradiol in the development of pulmonary arterial hypertension.Semantic proximity Read ↗

Interaction between Bone Morphogenetic Protein Receptor Type 2 and Estrogenic Compounds in Pulmonary Arterial HypertensionSemantic proximity Read ↗

Sex Dimorphism in Pulmonary Arterial Hypertension Associated With Autoimmune Diseases.Semantic proximity Read ↗

Epigenetic Regulation of Pulmonary Arterial Hypertension-Induced Vascular and Right Ventricular Remodeling: New Opportunities?Semantic proximity Read ↗

Hypoxia‐induced pulmonary hypertension upregulates eNOS and TGF‐β contributing to sex‐linked differences in BMPR2+/R899X mutant miceSemantic proximity Read ↗

Molecular biology of primary pulmonary hypertension.Semantic proximity Read ↗

Pulmonary arterial hypertension in women.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.