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Human Omental Mesothelial Cells Exhibit a Corneal Endothelial-Like Cell Phenotype for Tissue Engineering of a Corneal Endothelium Biomimetic.

Investigative ophthalmology & visual science - 1 Aug 2025

Alió Jorge L, Gauthier Benoit R, Gómez Rosado Juan C, Alió Del Barrio Jorge L, Rodríguez Alejandra E, Díaz Corrales Francisco J, Capitán Morales Luis C, Soria Bernat, Lachaud Christian C

Abstract excerpt

Purpose: To evaluate whether cultured human omental mesothelial cells (OMC) exhibit phenotypic and functional similarities to human corneal endothelial cells (CEC) and whether they can adhere to the corneal stroma and form a biomimetic corneal endothelium when grown on a human anterior lens capsule (HALC). Methods: Human OMC were isolated from the greater omentum. Human B4G12 CEC were used as a reference for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40762540
DOI: 10.1167/iovs.66.11.7
PMCID: PMC12347251

Genes

MSC
AQP1
ATP1A1
CD44
COL4A2
COL8A2
SLC4A11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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