Article
High-Quality Plant Genomes for and through Pangenomics.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2025
Papastolopoulou Christina, Yang Zijiang, van Workum Dirk-Jan M, Wijfjes Raúl Y, Smit Sandra
Abstract excerpt
The field of comparative genomics is shifting toward pangenomics, aiming to alleviate the reference bias observed in reference-based approaches. High-quality genomes are needed as input for pangenomics, as explained by the principle of "garbage in, garbage out". Errors in an assembly or annotation will lead to technical variation in a pangenome, while it is meant to reveal genuine biological variation only....
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