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Genetic Prediction of Causal Association Between Celiac Disease and Thyroid Function: A Two-Sample Mendelian Randomized Study

Endocrine, metabolic & immune disorders drug targets - 1 Jan 2026

He Xiaoshun, Lv Hanxin, Yu Wangjianfei, He Jun, Xie Yuyang, Zhou Lihao, Wu Hua, Guo Lingchuan, Yang Xiaoqin

Abstract excerpt

AIM: Observational studies have suggested an association between celiac disease and thyroid dysfunction, but their causal relationship has not yet been established. METHODS: Summary statistics for celiac disease were retrieved from the FinnGen Consortium, thyroid hormone and antibody data were obtained from the ThyroidOmics Consortium, and genetic variants associated with hyperthyroidism and hypothyroidism were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40735990
DOI: 10.2174/0118715303364014250713045734

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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