Are head and neck versus abdominal paragangliomas driven by different single nucleotide events?

doi:10.1007/s13353-025-00994-0

Article

Are head and neck versus abdominal paragangliomas driven by different single nucleotide events?

Journal of applied genetics - 1 Sept 2026

Kotlarz Krzysztof, Ziemnicka Katarzyna, Budny Bartłomiej, Mielczarek Magda, Liu Jakub, Wrotkowska Elżbieta, Kaznowski Jarosław, Suchocki Tomasz, Kałużny Jarosław, Wierzbicka Małgorzata, Dobosz Paula, Ruchała Marek, Szyda Joanna

Abstract excerpt

Paragangliomas (PGLs) are a heterogeneous group of tumours of the nonepithelial neuroendocrine type, with a significant percentage being genetically determined. They can develop from cells of the parasympathetic as well as the sympathetic nervous system. Tumours located in the head and neck usually have a parasympathetic origin, whereas those in the abdomen have a sympathetic origin. The aim of this study was to...

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Topics

Humans
Polymorphism, Single Nucleotide
Paraganglioma
Head and Neck Neoplasms
Abdominal Neoplasms

Are head and neck versus abdominal paragangliomas driven by different single nucleotide events?

Abstract excerpt

Topics

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