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Article

ALK-positive adult histiocytosis with a TFG-ALKfusion gene

23 Jul 2025

Abstract excerpt

ALK-positive histiocytosis is a rare condition that can affect multiple systems in infants and adults. We identified a rare case of ALK-positive histiocytosis with fusion of the ALK gene with TFG. A 35-year-old previously healthy male has been complaining of back and hip discomfort for seven months. A radiologic examination of the spine and pelvis revealed several hypermetabolic osteolytic lesions. Immunostaining...

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PMID: 40700600
DOI: 10.1093/oncolo/oyaf221

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