Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Integrative immune analysis in patients with leprosy reveals host factors associated with mycobacterial control

18 Jul 2025

Abstract excerpt

BACKGROUND: Leprosy is a debilitating, chronic infectious disease, ranking second after tuberculosis in the order of severe human mycobacterial diseases. If timely treatment is not initiated, infection with its causative agent, Mycobacterium leprae, can result in severe nerve damage leading to life-long disabilities. Host immunity largely dictates the spectral disease presentation, ranging from multi- to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Leprosy Research and Treatment
Share to Mycobacterium research and diagnosis
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40683203
DOI: 10.1016/j.ebiom.2025.105855

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 15 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Integrative immune analysis in patients with leprosy reveals host factors associated with mycobacterial controlPMID 40683203Read ↗

Functional biomarker signatures of circulating T-cells and its association with distinct clinical status of leprosy patients and their respective household contactsSemantic proximity Read ↗

In search of biomarkers for leprosy by unraveling the host immune response to Mycobacterium lepraeSemantic proximity Read ↗

A new paradigm for leprosy diagnosis based on host gene expression Insights from leprosy lesions transcriptomicsSemantic proximity Read ↗

The immune-suppressive landscape in lepromatous leprosy revealed by single-cell RNA sequencingSemantic proximity Read ↗

Single Cell and Spatial Transcriptomics Defines the Cellular Architecture of the Antimicrobial Response Network in Human Leprosy GranulomasSemantic proximity Read ↗

The continuing challenges of leprosy.Semantic proximity Read ↗

A new paradigm for leprosy diagnosis based on host gene expressionSemantic proximity Read ↗

Dual RNAseq of human leprosy lesions identifies bacterial determinants linked to host immune responseSemantic proximity Read ↗

Dual RNA-Seq of Human Leprosy Lesions Identifies Bacterial Determinants Linked to Host Immune ResponseSemantic proximity Read ↗

Mycobacterium leprae-host-cell interactions and genetic determinants in leprosy: an overview.Semantic proximity Read ↗

New pathways of protective and pathological host defense to mycobacteria.Semantic proximity Read ↗

The cellular architecture of the antimicrobial response network in human leprosy granulomasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.