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Article

Clinical heterogeneity and phenotyping of post cardiac arrest brain injury: one size may not fit all.

Intensive care medicine - 1 Jul 2025

Sekhon Mypinder S, Taccone Fabio Silvio, Skrifvars Markus B, Griesdale Donald E, Elmer Jonathan, Velly Lionel, Robba Chiara

Abstract excerpt

Post-cardiac arrest brain injury (PCABI) emanates from the injurious pathophysiologic sequelae that take place during and after resuscitation from cardiac arrest. Regrettably, identification of efficacious management strategies to mitigate PCABI has been disappointing with numerous well-conducted randomized control trials yielding neutral results. The reasons for this observation are likely multifactorial,...

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PMID: 40668231
DOI: 10.1007/s00134-025-08012-x
PMCID: PMC12283859

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