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Article

Machine learning derivation of two cardiac arrest subphenotypes with distinct responses to treatment.

Journal of translational medicine - 6 Jan 2025

Zhang Weidong, Wu Chenxi, Ni Peifeng, Zhang Sheng, Zhang Hongwei, Zhu Ying, Hu Wei, Diao Mengyuan

Abstract excerpt

INTRODUCTION: Cardiac arrest (CA), characterized by its heterogeneity, poses challenges in patient management. This study aimed to identify clinical subphenotypes in CA patients to aid in patient classification, prognosis assessment, and treatment decision-making. METHODS: For this study, comprehensive data were extracted from the Medical Information Mart for Intensive Care IV (MIMIC-IV) 2.0 database. We excluded...

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PMID: 39762860
DOI: 10.1186/s12967-024-05975-1

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