Derivatives of the triglyceride–glucose index and their association with incident hypertension in prehypertensive individuals: a 4-year cohort study augmented by mendelian randomization

Abstract excerpt

BACKGROUND: The direct association between elevated levels of the triglyceride-glucose index (TyG index) and its derived metrics and the risk of new-onset hypertension in prehypertensive populations remains unclear. The study systematically evaluated the link between the TyG index and its related indicators with new-onset hypertension by integrating cohort study methods with Mendelian randomization (MR) analysis....

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• Adipokines, Inflammation, and Metabolic Diseases
• Diabetes, Cardiovascular Risks, and Lipoproteins
• Genetic Associations and Epidemiology