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Article

Label-free metabolic imaging and energy costs in Chlamydomonas.

The European physical journal. E, Soft matter - 11 Jul 2025

Boccara Martine, Wostrikoff Katia, Bailleuil Benjamin, Boccara Claude

Abstract excerpt

We developed a label-free optical microscopy method to study movements of different frequencies and amplitudes within a cell. We use optical transmission tomography (OTT) that operates in transmission, and we record the changes of signal values of all the pixels of movies taken for a few seconds (dynamic signal). This signal is a metabolic signal in algae as it decreased in the presence of photosystem II...

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Identifiers

PMID: 40643810
DOI: 10.1140/epje/s10189-025-00499-y
PMCID: PMC12254062

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