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Genetic Determinants of Leisure-Time Physical Activity in the Taiwanese Population: A Genome-Wide Association Study.

Medicine and science in sports and exercise - 1 Dec 2025

Hsu Lung-An, Wu Semon, Tran Ngoc Yen, Chou Hsin-Hua, Ko Yu-Lin

Abstract excerpt

BACKGROUND: Physical inactivity contributes to systemic disease burden and premature mortality worldwide. Leisure-time physical activity (LTPA) improves health outcomes; however, its genetic determinants, particularly in Asian populations, remain unclear. This study aimed to identify genetic loci associated with LTPA in the Taiwanese population. METHODS: We conducted genome-wide association studies in 122,258...

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Identifiers

PMID: 40638807
DOI: 10.1249/MSS.0000000000003815
PMCID: PMC12893172

Genes

ALDH2
ATXN2
FTO
MET
NOTCH4
BRAP

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