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Article

Predicting adolescent disordered eating and behaviours: exploring environmental moderators of polygenic risk.

Journal of child psychology and psychiatry, and allied disciplines - 1 Dec 2025

Curtis Madeleine, Colodro-Conde Lucia, Medland Sarah E, Gordon Scott, Martin Nicholas G, Wade Tracey D, Cohen-Woods Sarah

Abstract excerpt

BACKGROUND: Both genetic and environmental factors contribute to the risk of developing disordered eating, with twin studies demonstrating environmental factors moderate genetic susceptibility. To date, gene-environment interactions leveraging polygenic risk scores (PRS) have not been studied in disordered eating phenotypes beyond anorexia nervosa (AN). This study investigated if polygenic risk for AN interacts...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40633822
DOI: 10.1111/jcpp.70012
PMCID: PMC12626179

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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