Overexpression of Aquaporin‐1 Promotes Epithelial–Mesenchymal Transition and Cancer Stem Cell Properties via Wnt/β‐Catenin Signaling Pathway in Advanced Breast Cancer Cells

Abstract excerpt

Tumor metastasis and the persistence of cancer stem cells (CSCs) are the main factors contributing to tumor malignancy, particularly in breast cancer. Uncovering the critical molecular mechanisms and therapeutic targets is essential for addressing this challenge. The present study revealed that aquaporin-1 (AQP1) was highly expressed in breast cancer and was closely associated with poor patient prognosis. AQP1...

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