Tiered approach to molecular testing of thyroid fine needle aspiration samples may improve preoperative diagnosis.

doi:10.1016/j.ejso.2025.110082

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Article

Tiered approach to molecular testing of thyroid fine needle aspiration samples may improve preoperative diagnosis.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology - 1 Sept 2025

George Nelson, Chu Simon, Manning Stephanie, Lim Kai-Zheong, Mond Michael, Tay Ernest, Yellapu Bhargavi, Jones Kate, Fellowes Andrew, Kumar Beena, Serpell Jonathan, Grodski Simon, Shackleton Mark, Yannakou Costas K, Lee James C

Abstract excerpt

BACKGROUND: Patients with indeterminate thyroid nodules continue to be a challenge to clinicians. Molecular testing on fine needle aspirates (FNA) is well established in the United States, but its access is limited elsewhere. We aimed to explore the utility of a pre-existing Next Generation Sequencing (NGS) platform, and the role of BRAF mutation in patient selection for preoperative molecular testing. METHODS:...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to High-Throughput Nucleotide Sequencing

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Share to Proto-Oncogene Proteins B-raf

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Identifiers

PMID: 40614342
DOI: 10.1016/j.ejso.2025.110082

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BRAF

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