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Mechanisms of azithromycin resistance in Salmonella Typhi: molecular insights from dynamics behavior to clinical implications.

Journal of biomolecular structure & dynamics - 1 Feb 2026

Farishta Syeda, Faryal Rani, Waqas Muhammad, Ali Muhammad, Uppal Rizwan, Salman Muhammad, Ashraf Zurva, Khalid Asaad, Khan Ajmal

Abstract excerpt

The widespread use of azithromycin during the COVID-19 pandemic has likely contributed to the increased resistance of Salmonella Typhi to this antibiotic. This study focuses on the extensive drug resistance (XDR) of Salmonella Typhi in Pakistan, analyzing 11,916 suspected typhoid fever cases, with 424 confirmed as Salmonella Typhi and Paratyphi A. Through antimicrobial susceptibility tests and PCR-based Sanger...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40607646
DOI: 10.1080/07391102.2025.2524407

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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