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Breastfeeding and early Bifidobacterium-driven microbial colonization shape the infant gut resistome

2 Jul 2025

Abstract excerpt

The assembly of the gut resistome in early life is key to infant health. Specific perinatal factors such as cesarean section (C-section), antibiotic exposure and lack of breastfeeding practices are detrimental to proper microbial development and increase the antimicrobial resistance genes (ARGs). Using 265 gut longitudinal metagenomes from 66 mother-infant pairs, we investigated how perinatal factors influence...

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PMID: 40603287
DOI: 10.1038/s41467-025-61154-w

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