Comprehensive characterization of NK cell-related genes in cutaneous melanoma identified a novel prognostic signature for predicting the prognosis, immunotherapy, and chemotherapy efficacy

Abstract excerpt

BACKGROUND: Natural killer (NK) cells, as key effectors of the innate immune system, play a crucial role in cancer prognosis and immunotherapy. This study aimed to develop a predictive model based on NK cell-associated immune genes (NKIGs) for patients with cutaneous melanoma (CM) and to assess its utility in predicting prognosis and guiding personalized treatment. METHODS: RNA-sequencing data and clinical...

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