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Cholesterol's hidden impact: the nonlinear link between remnant cholesterol (RC) and phenotypic age acceleration (PhenoAgeAccel).

Biogerontology - 27 Jun 2025

Yang QianKun, Zhu Shan, Luo YanFang, Ai HongBo, Feng Lei, Zhang Li, Luo Fei

Abstract excerpt

Cholesterol metabolism disorders have been shown to correlate with multiple physiopathologic aspects of cellular aging. However, whether indicators reflecting cholesterol metabolism [e.g., remnant cholesterol (RC)] can serve as biomarkers for biological aging remains unclear. To address this gap, this study aimed to explore the relationship between RC and phenotypic age acceleration (PhenoAgeAccel) using data...

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PMID: 40579661
DOI: 10.1007/s10522-025-10266-3

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