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Article

Maternal modifiers of the infant gut microbiota: metabolic consequences

27 Jul 2017

Abstract excerpt

Transmission of metabolic diseases from mother to child is multifactorial and includes genetic, epigenetic and environmental influences. Evidence in rodents, humans and non-human primates support the scientific premise that exposure to maternal obesity or high-fat diet during pregnancy creates a long-lasting metabolic signature on the infant innate immune system and the juvenile microbiota, which predisposes the...

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PMID: 28751453
DOI: 10.1530/joe-17-0303

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