Article
Genotype-Environment-Driven Dysbiosis in the Skin Microbiome of Ichthyosis.
The Journal of investigative dermatology - 1 Feb 2026
Zhou Wei, Ring Nan G, Caldwell Ryan, Milstone Leonard M, Oh Julia
Abstract excerpt
Many factors might be expected to influence the cutaneous microbiome, especially on diseased skin. Yet, few studies account for the complex interactions between host and environmental factors. To shed light on such interactions, we characterized the skin microbiome from 7 types of ichthyosis and confirmed previous reports of genotype-related and barrier-related effects. We then focused on the TGM1 genotype and...
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