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Article

Association of RBD mutations with COVID-19 disease severity in the Iranian population.

Virus genes - 1 Oct 2025

Mondeali Mozhgan, Mahjoor Mohamad, Khaledi Mansoor, Saghabashi Ahdiyeh, Rostami Seyedeh Faride Alavi, Modarressi Mohammad Hossein

Abstract excerpt

The global public health is still at risk due to the COVID-19 pandemic, which was caused by SARS-CoV-2. Disease severity varies among patients and is influenced by mutations in the viral genome, particularly within the spike protein's receptor-binding domain (RBD). This study aimed to investigate the association between RBD mutations and disease severity and to shed light on the fundamental molecular mechanisms....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40569496
DOI: 10.1007/s11262-025-02168-w

Genes

ACE2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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